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Antigenic Specificity | IL2RA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total IL2RA protein. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human interleukin 2 receptor, alpha |
Other Names | [CD25; IL2R; TCGFR; IDDM10] |
Gene, Accession # | [IL2RA], Gene ID: 3559, NCBI: NP_000408.1, UniProt: P01589 |
Catalog # | MBS9410744 |
Price | $255 |
Order / More Info | IL2RA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |