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Antigenic Specificity | Caspase 10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody reacts with human Caspase-10. The other species are not tested. A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6 and caspase-7, caspase-9, and caspase-10. Ced-3 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli. |
Immunogen | n/a |
Other Names | [CASP10], [CASP10; CASP10; MCH4; ALPS2; FLICE2; MCH4; CASP-10; FLICE2] |
Gene, Accession # | Gene ID: 843, NCBI: CAD32372.1, UniProt: Q92851 |
Catalog # | MBS460030 |
Price | $285 |
Order / More Info | Caspase 10 Antibody from MYBIOSOURCE INC. |
Product Specific References | Muhlethaler-Mottet, A., Flahaut, M., Bourloud, K.B., Nardou, K., Coulon, A., Liberman, J., Thome, M. and Gross, N. Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-mediated tumour cell apoptosis. Cell Death Dis 2, E125 (2011). |