Caspase 10 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase 10
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionThis antibody reacts with human Caspase-10. The other species are not tested. A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6 and caspase-7, caspase-9, and caspase-10. Ced-3 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli.
Immunogenn/a
Other Names[CASP10], [CASP10; CASP10; MCH4; ALPS2; FLICE2; MCH4; CASP-10; FLICE2]
Gene, Accession #Gene ID: 843, NCBI: CAD32372.1, UniProt: Q92851
Catalog #MBS460030
Price$285
Order / More InfoCaspase 10 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMuhlethaler-Mottet, A., Flahaut, M., Bourloud, K.B., Nardou, K., Coulon, A., Liberman, J., Thome, M. and Gross, N. Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-mediated tumour cell apoptosis. Cell Death Dis 2, E125 (2011).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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