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Antigenic Specificity | ZNF536 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ZNF536 Antibody: ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus. ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription. It is most closely related to transcriptional repressor ZNF219. Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and beta-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation. Overexpression of RA receptor a rescues the inhib |
Immunogen | Immunogen: ZNF536 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human ZNF536. Buffer: ZNF536 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ZNF536; KIAA0390; Zinc finger protein 536; zinc finger protein 536], [ZNF536; ZNF536; KIAA0390] |
Gene, Accession # | [ZNF536], Gene ID: 9745, NCBI: NP_055532.1, UniProt: O15090 |
Catalog # | MBS150992 |
Price | $375 |
Order / More Info | ZNF536 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |