KRIT1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKRIT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC)
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DescriptionThis gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this
ImmunogenImmunogen: Recombinant protein of human KRIT1 (NP 919438.1).
Other Names[krev interaction trapped protein 1 isoform 2; Krev interaction trapped protein 1; krev interaction trapped protein 1; KRIT1 ankyrin repeat containing; Cerebral cavernous malformations 1 protein]
Gene, Accession #[KRIT1], Gene ID: 889, NCBI: NP_001013424.1, UniProt: O00522
Catalog #MBS8571016
Price$280
Order / More InfoKRIT1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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