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Antigenic Specificity | FOS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Fos family of nuclear oncogenes includes c-Fos, FosB, Fos-related antigen 1 (FRA1), and Fos-related antigen 2 (FRA2) (1). While most Fos proteins exist as a single isoform, the FosB protein exists as two isoforms: full-length FosB and a shorter form, FosB2 (Delta FosB), that lacks the carboxy-terminal 101 amino acids (1-3). The expression of Fos proteins is rapidly and transiently induced by a variety of extracellular stimuli including growth factors, cytokines, neurotransmitters, polypeptide hormones, and stress. Fos proteins dimerize with Jun proteins (c-Jun, JunB, and JunD) to form Activator Protein-1 (AP-1), a transcription factor that binds to TRE/AP-1 elements and activates transcription. Fos and Jun proteins contain the leucine-z |
Immunogen | Immunogen: Center-peptide of human FOS Observed Molecular Weight: 41kDa |
Other Names | [FOS; AP-1; C-FOS; Proto-oncogene c-Fos] |
Gene, Accession # | [FOS], Gene ID: 2353, NCBI: CAG47063.1, UniProt: Q6FG41 |
Catalog # | MBS2518992 |
Price | $150, $225, $360 |
Order / More Info | FOS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |