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Antigenic Specificity | Human CD95 (Fas/Apo-1) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/200ul |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CD95/Fas/Apo-1. CD95, also known as Fas and Apo-1, is a 40-50 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance. Crosslinking of CD95 by the monoclonal antibodies DX2 and DX3 delivers an apoptotic signal to Fas-sensitive cells, indicating that these monoclonal antibodies recognize a functional epitope of CD95. |
Immunogen | n/a |
Other Names | [CD95 antigen, partial; CD95 antigen; tumor necrosis factor receptor superfamily member 6; Fas cell surface death receptor; CD95 antigen] |
Gene, Accession # | [CD95], Gene ID: 355, NCBI: CAC35541.1, UniProt: Q9UEL0 |
Catalog # | MBS4152214 |
Price | $445 |
Order / More Info | Human CD95 (Fas/Apo-1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |