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Antigenic Specificity | MCL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MCL1 protein. Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.Alfredo De Biasio, J. Biol. Chem., Jun 2007; 10.1074.Potchanapond Graidist, J. Biol. Chem., Sep 2004; 279: 40868 - 40875. Kenichi Fujise, J. Biol. Chem., Dec 2000; 275: 39458. Di Zhang, J. Biol. Chem., Sep 2002; 277: 37430 - 37438. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human MCL1. |
Other Names | [EAT/MCL-1 protein; Induced myeloid leukemia cell differentiation protein Mcl-1; Myeloid cell leukemia sequence 1.] |
Gene, Accession # | [MCL1], Gene ID: 4170, NCBI: NP_001184249.1, UniProt: Q07820 |
Catalog # | MBS9401786 |
Price | $200, $255 |
Order / More Info | MCL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |