Edit |   |
---|---|
Antigenic Specificity | HNF4 alpha (phospho-Ser304) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunoblotting (IB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous human, mouse, and rat HNF4alpha only when phosphorylated at serine 304. Hepatocyte nuclear factor 4 alpha (HNF4alpha) is a nuclear transcription factor that binds DNA as a homodimer and controls the expression of several genes including hepatocyte nuclear factor 1, a transcripton factor that regulates expression of several hepatic genes. HNF4alpha has been implicated in development of liver, kidney, and intestines. Mutations in the HNF4alpha gene have been associated with monogenic autosomal-dominant non-insulin-dependent diabetes mellitus type 1. Alternative splicing of this gene results in multiple transcript variants. |
Immunogen | Antigen: Peptide sequence that includes phosphorylation site of serine 304 (L-R-S(p)-Q-V) derived from human HNF4alpha and conjugated to KLH. |
Other Names | [hepatocyte nuclear factor 4-alpha 2; Hepatocyte nuclear factor 4-alpha; hepatocyte nuclear factor 4-alpha; hepatocyte nuclear factor 4 alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14; TCF-14; Transcription factor HNF-4], [HNF4A; HNF4A; TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; HNF4alpha; HNF4; NR2A1; TCF14; HNF-4-alpha; TCF-14] |
Gene, Accession # | [HNF4 alpha], Gene ID: 3172, NCBI: NP_000448.3, UniProt: P41235 |
Catalog # | MBS191055 |
Price | $340 |
Order / More Info | HNF4 alpha (phospho-Ser304) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |