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Antigenic Specificity | NPTX2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NPTX2 Antibody: Neuronal pentraxin (NPTX) 2 was initially identified as a member of the pentraxin family having high homology to NPTX1. Unlike NPTX1 however, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle as well as brain. NPTX2 possesses the lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes that contribute to both activity-independent and -dependent excitatory synaptogenesis. Recently, NPTX2 has been found to be highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and Lewy neurites in sporadic Parkinson's disease (PD), suggesting that it is involved in the pathway dysregulation t |
Immunogen | Immunogen: NPTX2 antibody was raised against a 16 amino acid synthetic peptide near the center of the human NPTX2. Buffer: NPTX2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [NPTX2; NP2; NARP; NP-II; Neuronal pentraxin-2; Neuronal pentraxin II; NP2; neuronal pentraxin II], [NPTX2; NPTX2; NP2; NARP; NP-II; NP2; NP-II] |
Gene, Accession # | [NPTX2], Gene ID: 4885, NCBI: NP_002514, UniProt: P47972 |
Catalog # | MBS150863 |
Price | $375 |
Order / More Info | NPTX2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |