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Antigenic Specificity | SEC24D |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 3.77 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 830-1000 of human SEC24D (NP 001304995.1). Immunogen Sequence: AASQLILPDSMKVLPVYMNCLLKNCVLLSRPEISTDERAYQRQLVMTMGVADSQLFFYPQLLPIHTLDVKSTMLPAAVRCSESRLSEEGIFLLANGLHMFLWLGVSSPPELIQGIFNVPSFAHINTDMTLLPEVGNPYSQQLRMIMGIIQQKRPYSMKLTIVKQREQPEMV |
Other Names | [SEC24D; CLCRP2; protein transport protein Sec24D] |
Gene, Accession # | [SEC24D], Gene ID: 9871, NCBI: NP_055637, UniProt: O94855 |
Catalog # | MBS9140709 |
Price | $260 |
Order / More Info | SEC24D Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |