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Antigenic Specificity | KRAS, 1-188 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KRAS, also called p21, is a member of the Ras superfamily of proteins. It is located on human chromosome 12, and contains four coding exons and a 5' non-coding exon (PMID: 12778136). KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family, the KRAS protein is a GTPase, and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation (PMID: 19117687). KRAS mutations have been found in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. KRAS has two isoforms, a and b. |
Immunogen | Immunogen: Recombinant Protein of Human pan Ras, at AA range: 1-188aa |
Other Names | [C K RAS; c Ki ras; GTPase KRas; K Ras 2; K RAS2A; K RAS2B; K RAS4A; K RAS4B; KI RAS; KRAS; KRAS1; KRAS2; KRAS2A; KRAS2B; KRAS2B speicifc; Krasa; Krasb; NS3; RASK2] |
Gene, Accession # | [KRAS], Gene ID: 3845, NCBI: NP_004976.2, UniProt: P01116 |
Catalog # | MBS2540207 |
Price | $220, $290, $435 |
Order / More Info | KRAS, 1-188 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |