KRAS, 1-188 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKRAS, 1-188
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionKRAS, also called p21, is a member of the Ras superfamily of proteins. It is located on human chromosome 12, and contains four coding exons and a 5' non-coding exon (PMID: 12778136). KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family, the KRAS protein is a GTPase, and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation (PMID: 19117687). KRAS mutations have been found in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. KRAS has two isoforms, a and b.
ImmunogenImmunogen: Recombinant Protein of Human pan Ras, at AA range: 1-188aa
Other Names[C K RAS; c Ki ras; GTPase KRas; K Ras 2; K RAS2A; K RAS2B; K RAS4A; K RAS4B; KI RAS; KRAS; KRAS1; KRAS2; KRAS2A; KRAS2B; KRAS2B speicifc; Krasa; Krasb; NS3; RASK2]
Gene, Accession #[KRAS], Gene ID: 3845, NCBI: NP_004976.2, UniProt: P01116
Catalog #MBS2540207
Price$220, $290, $435
Order / More InfoKRAS, 1-188 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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