AIRE - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAIRE - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against AIRE. It was validated on Western Blot and immunohistochemistryTarget Description: The function of the protein encoded by the AIRE gene is not well defined. However it contains zinc finger motifs suggestive of a transcription factor. The protein (isoform 1) is localized to both the nucleus and cytoplasm. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a prematu
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AIRE
Other Names[autoimmune regulator; Autoimmune regulator; autoimmune regulator; autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein]
Gene, Accession #[AIRE], Gene ID: 326, NCBI: NP_000374, UniProt: O43918
Catalog #MBS3201075
Price$335
Order / More InfoAIRE - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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