Edit |   |
---|---|
Antigenic Specificity | AIRE - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against AIRE. It was validated on Western Blot and immunohistochemistryTarget Description: The function of the protein encoded by the AIRE gene is not well defined. However it contains zinc finger motifs suggestive of a transcription factor. The protein (isoform 1) is localized to both the nucleus and cytoplasm. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a prematu |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AIRE |
Other Names | [autoimmune regulator; Autoimmune regulator; autoimmune regulator; autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein] |
Gene, Accession # | [AIRE], Gene ID: 326, NCBI: NP_000374, UniProt: O43918 |
Catalog # | MBS3201075 |
Price | $335 |
Order / More Info | AIRE - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |