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Antigenic Specificity | SMARCA4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total SMARCA4 protein. The modulation of chromatin structure is an essential component in the regulation of transcriptional activation and repression. Modifications can be made by at least two evolutionarily conserved strategies, through the disruption of histone-DNA contacts by ATP-dependent chromatin remodelers, or by histone tail modifications including methylation and acetylation. One of the four classes of ATP-dependent histone remodelers is the SWI/SNF complex, the central catalytic subunit of which is Brg1 or the highly related protein hBRM (1). This SWI/SNF complex contains varying subunits but its association with either Brg1 or hBRM remains constant (1). SWI/SNF complexes have been shown to |
Immunogen | Immunogen Type: Peptide Immunogen Description: A synthetic peptide of human SMARCA4. |
Other Names | [BAF190; BRG1; FLJ39786; SNF2; SNF2-BETA] |
Gene, Accession # | [SMARCA4], Gene ID: 6597, NCBI: NP_001122316.1, UniProt: P51532 |
Catalog # | MBS9403117 |
Price | $255 |
Order / More Info | SMARCA4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |