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Antigenic Specificity | MRGPRX2 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MRGPRX2. It was validated on Western BlotTarget Description: MRGPRX2 is an orphan receptor. It probably involved in the function of nociceptive neurons. It also may regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca2+ but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MRGPRX2 |
Other Names | [mas-related G-protein coupled receptor member X2; Mas-related G-protein coupled receptor member X2; mas-related G-protein coupled receptor member X2; MAS related GPR family member X2] |
Gene, Accession # | [MRGPRX2], Gene ID: 117194, NCBI: NP_473371, UniProt: Q96LB1 |
Catalog # | MBS3214566 |
Price | $335 |
Order / More Info | MRGPRX2 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |