Axin1 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAxin1 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, human
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against Axin1. It was validated on Western BlotTarget Description: Axin1 is a component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Axin1 controls dorsoventral patterning via two opposing effects; down-regulates beta-catenin to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. It also facilitates the phosphorylation of APC by GSK3B, facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation and enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting th
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Axin1
Other Names[Axin-1; axin-1; axin 1; Axis inhibition protein 1; rAxin]
Gene, Accession #[AXIN1], Gene ID: 12005, NCBI: XP_920000, UniProt: O70239
Catalog #MBS3206591
Price$335
Order / More InfoAxin1 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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