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Antigenic Specificity | Axin1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Axin1. It was validated on Western BlotTarget Description: Axin1 is a component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Axin1 controls dorsoventral patterning via two opposing effects; down-regulates beta-catenin to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. It also facilitates the phosphorylation of APC by GSK3B, facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation and enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting th |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Axin1 |
Other Names | [Axin-1; axin-1; axin 1; Axis inhibition protein 1; rAxin] |
Gene, Accession # | [AXIN1], Gene ID: 12005, NCBI: XP_920000, UniProt: O70239 |
Catalog # | MBS3206591 |
Price | $335 |
Order / More Info | Axin1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |