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Antigenic Specificity | Hsp40, YDJ1 |
Clone | [1G10.H8] |
Host Species | Mouse |
Reactive Species | yeast. does not cross react with human, mouse or rat. |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 0.025 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects ~40kDa. Scientific Background: Human Hsp40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein) (1). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain (2). There are two main types of Hsp40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding. (3, 4), type II does not. Members of the Hsp40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. |
Immunogen | n/a |
Other Names | [DNAJA2; CPR3; HIRIP4; DNAJ; DNJ3; DJ3; RDJ2; HIRa interatcting protein4], [YDJ1; YDJ1; HSP40; MAB3; MAS5; MAS5; YNL064C; N2418; YNL2418C] |
Gene, Accession # | Gene ID: 855661, NCBI: NP_014335.1, UniProt: P25491 |
Catalog # | MBS800241 |
Price | $255 |
Order / More Info | Hsp40, YDJ1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Cheetham M.E. and Caplan A.J. (1998) Cell Stress Chaperones 3: 28-36. 2. Fan C.Y., et al. (2003) Cell Stress Chaperones 8: 309-316. 3. Terda K., et al. (1997) J Cell Biol. 139: 1089-1095. 4. Lu Z. and Cyr D.M. (1998) J Biol Chem. 273: 27824-27830. 5. Liberek K. et al. (1991) Proc. Natl. Acad. Sci. USA 88: 2874-2878. 6. Cyr D.M., et al. (1992) J Biol Chem. 267: 20927-20931. 7. Hohfeld J., et al. (2001) EMBO Rep. 2: 885-890. |