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Antigenic Specificity | Dok-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Dok-2 Polyclonal Antibody detects endogenous levels of Dok-2 protein. Docking protein 2 encoded by DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 2 binds p120 (RasGAP) from CML cells. |
Immunogen | Immunogen: Synthesized peptide derived from human Dok-2 around the non-phosphorylation site of Y299 |
Other Names | [Rabbit Dok-2; DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2)] |
Gene, Accession # | [DOK-2], Gene ID: 9046, NCBI: NP_003965.2, UniProt: O60496 |
Catalog # | MBS9701903 |
Price | $130, $220, $325 |
Order / More Info | Dok-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |