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Antigenic Specificity | Cdc42EP5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Cdc42EP5 Polyclonal Antibody detects endogenous levels of Cdc42EP5 protein. Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts. |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human Cdc42EP5 at AA range: 1-80 |
Other Names | [Rabbit Cdc42EP5; CDC42EP5; BORG3; CEP5; Cdc42 effector protein 5; Binder of Rho GTPases 3] |
Gene, Accession # | [CDC42EP5], Gene ID: 148170, NCBI: NP_659494.2, UniProt: Q6NZY7 |
Catalog # | MBS9701657 |
Price | $130, $220, $325 |
Order / More Info | Cdc42EP5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |