IFT57 (Center) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | IFT57 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | humanpredicted: bovine |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This IFT57 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 159-193 amino acids from the Central region of human IFT57. Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); Intraflagellar transport protein 57 homolog; Dermal papilla-derived protein 8; Estrogen-related receptor beta-like protein 1; HIP1-interacting protein; MHS4R2; IFT57; DERP8; ESRRBL1; HIPPI] |
| Gene, Accession # | [IFT57], Gene ID: 55081, NCBI: NP_060480.1, UniProt: Q9NWB7 |
| Catalog # | MBS9231307 |
| Price | $165, $370 |
| Order / More Info | IFT57 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Gervais F.G.,et al.Nat. Cell Biol. 4:95-105(2002). Pasutto F.,et al. Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases. Ikeda A.,et al. Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Ebert L.,et al. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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