Edit |   |
---|---|
Antigenic Specificity | SEPT2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total SEPT2 protein. Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of t |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human SEPT2. |
Other Names | [DIFF6; NEDD5; NEDD-5; Pnutl3; hNedd5] |
Gene, Accession # | [SEPT2], Gene ID: 4735, NCBI: NP_001008491.1, UniProt: Q15019 |
Catalog # | MBS9401401 |
Price | $255 |
Order / More Info | SEPT2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |