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Antigenic Specificity | Human Heat Shock Transcription Factor-1 |
Clone | [PJ7F9AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: The transcription of heat-shock genes is rapidly induced after temperature stress in response to environmental changes, and it is also involved in oogenesis, spermatogenesis, and placental development. Hsp90, is a major repressor of HSF1 gene. HSF1 is known for its participation in heat shock response. HSF1 protein regulates the transcription of hundreds of targets, such as genes involved in protein folding, detoxification, energy generation, carbohydrate metabolism, and cell wall organization. HSF1 binds to MTA1 in vitro & in breast carcinoma. Suppression of estrogen-dependent transcription may contribute to role of HSF1 in cancer. Human cancer lines of diverse origins express higher dependence on HSF1 function to maintain pr |
Immunogen | Immunogen: Anti-human HSF1 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSF1 amino acids 1-529 purified from E Coli. |
Other Names | [HSF1; Heat Shock Transcription Factor-1, Mouse Human; HSF-1; HSF1; HSTF-1; HSTF1; Heat shock factor protein 1; Heat shock transcription factor 1], [HSF1; HSF1; HSTF1; HSTF1; HSF 1; HSTF 1] |
Gene, Accession # | [HSF1], Gene ID: 3297, NCBI: NP_005517.1 |
Catalog # | MBS140262 |
Price | $140, $205, $505 |
Order / More Info | Human Heat Shock Transcription Factor-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |