Caspase-9 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase-9
Clone[1D1-F2-E9]
Host SpeciesMouse
Reactive Specieshuman, Transfected
IsotypeIgG1
Formataffinity purified
Size0.1 mL
Concentration8mg/ml
ApplicationsWestern Blot (WB)
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DescriptionEntrez Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing re
ImmunogenImmunogen: Purified recombinant human Caspase-9 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of Caspase-9 and does not cross-react with related proteins. Sequence Similarities: Belongs to the peptidase C14A family. Contains 1 CARD domain.
Other Names[APAF 3; APAF-3; APAF3; Apoptosis related cysteine peptidase; Apoptotic protease activating factor 3; Apoptotic protease Mch 6; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; CASP 9; CASP-9; CASP9; CASP9_HUMAN; Caspase 9 apoptosis related cysteine peptidase; Caspase 9 Dominant Negative; Caspase 9c; Caspase-9; Caspase-9 subunit p10; Caspase9; ICE LAP6; ICE like apoptotic protease 6; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9], [CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6]
Gene, Accession #[CASP9], Gene ID: 842, NCBI: NP_001220.2, UniProt: P55211
Catalog #MBS475166
Price$335
Order / More InfoCaspase-9 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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