ATP1A1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityATP1A1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe Na, K-ATPase is an integral membrane heterodimer belonging to the P-type ATPase family. This ion channel uses the energy derived from ATP hydrolysis to maintain membrane potential by driving sodium export and potassium import across the plasma membrane against their electrochemical gradients. It is composed of a catalytic alpha subunit and a beta subunit (reviewed in 1). Several phosphorylation sites have been identified for the alpha1 subunit. Tyr10 is phosphorylated by an as yet undetermined kinase (2), Ser16 and Ser23 are phosphorylated by PKC, and Ser943 is phosphorylated by PKA (3-5). All of these sites have been implicated in the regulation of enzyme activity in response to hormones and neurotransmitters, altering trafficking and
ImmunogenImmunogen: Fusion protein of human ATP1A1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[ATP1A1; MGC3285; MGC51750; Na; K-ATPase]
Gene, Accession #[ATP1A1], Gene ID: 476, NCBI: NP_000692.2, UniProt: P05023
Catalog #MBS8527342
Price$310
Order / More InfoATP1A1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Therien, A.G. and Blostein, R. (2000) Am. J. Physiol. Cell Physiol. 279, C541-566. 2. Feraille, E. et al. (1999) Mol. Biol. Cell 10, 2847-2859. 3. Fisone, G. et al. (1994) J. Biol. Chem. 269, 9368-9373. 4. Feschenko, M.S. and Sweadner, K.J. (1995) J. Biol. Chem. 270, 14072-14077. 5. Beguin, P. et al. (1994) J. Biol. Chem. 269, 24437-24445. 6. Yingst, D.R. et al. (2004) Am. J. Physiol. Renal Physiol. 287, F713-F721. 7. Al-Khalili, L. et al. (2004) J. Biol. Chem. 279, 25211-25218. 8. Tian, J. et al. (2006) Mol. Biol. Cell 17, 317-326. 9. Liang, M. et al. (2006) J. Biol. Chem. 281, 19709-19719.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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