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Antigenic Specificity | R Prkaa1 (N-term), 16-47 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.44 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Rat Prkaa1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-47 amino acids from the N-terminal region of rat Prkaa1. Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling |
Immunogen | n/a |
Other Names | [5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; Prkaa1; Ampk1] |
Gene, Accession # | [Prkaa1], Gene ID: 65248, NCBI: NP_062015.2, UniProt: P54645 |
Catalog # | MBS9201486 |
Price | $165, $370 |
Order / More Info | R Prkaa1 (N-term), 16-47 Antibody from MYBIOSOURCE INC. |
Product Specific References | Mural R.J., et al. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Stapleton D., et al. J. Biol. Chem. 271:611-614(1996). Clarke P.R., et al. EMBO J. 9:2439-2446(1990). Stapleton D., et al. J. Biol. Chem. 269:29343-29346(1994). Hawley S.A., et al. J. Biol. Chem. 271:27879-27887(1996). |