TMP21 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TMP21 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TMP21 Antibody: TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport. More recent experiments have shown that it is also a component in the presenilin complex and modulates the gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein. The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1. Together, these proteins cleave the amyloid precursor protein at what is known as the gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer's disease. Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indic |
| Immunogen | Immunogen: TMP21 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human TMP21. Buffer: TMP21 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [TMP21; p23; TMP21; S31I125; Tmp-21-I; S31III125; P24(DELTA); Transmembrane emp24 domain-containing protein 10; 21 kDa transmembrane-trafficking protein; transmembrane emp24-like trafficking protein 10 (yeast)], [TMED10; TMED10; p23; TMP21; S31I125; Tmp-21-I; S31III125; P24(DELTA); TMP21; S31I125; p24delta1] |
| Gene, Accession # | [TMED10], Gene ID: 10972, NCBI: AAD31941, UniProt: P49755 |
| Catalog # | MBS150954 |
| Price | $375 |
| Order / More Info | TMP21 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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