SkiP Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SkiP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SkiP Antibody: TGF-beta and the bone morphogenic proteins (BMPs) are key signaling proteins that regulate numerous cellular processes such as embryonic development and tumorigenesis. Both signal through the Smad protein family and are negatively regulated by Ski and SnoN, two related proto-oncoproteins. Ski functions by binding to the Smad proteins activated by TGF-beta and the (BMPs) and preventing their phosphorylation, inhibiting their ability to bind DNA and activate the transcription of downstream genes. SkiP was originally identified as a Ski-interacting protein and was later found to augment the signals induced by TGF-beta but inhibit transcription induced by BMP-2 in C2C12 cells, suggesting that SkiP is a key player in the signaling |
| Immunogen | Immunogen: SkiP antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human SkiP. Buffer: SkiP Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [SkiP; Bx42; SKIP; Prp45; SKIIP; PRPF45; NCOA-62; SNW domain-containing protein 1; Nuclear protein SkiP; SNW domain containing 1], [SNW1; SNW1; Bx42; SKIP; Prp45; SKIIP; PRPF45; NCOA-62; SKIIP; SKIP] |
| Gene, Accession # | [SNW1], Gene ID: 22938, NCBI: NP_036377, UniProt: Q13573 |
| Catalog # | MBS150270 |
| Price | $375 |
| Order / More Info | SkiP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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