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Antigenic Specificity | FKBP8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis. |
Immunogen | Immunogen: Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP8 protein (58-190AA) |
Other Names | [Peptidyl-prolyl cis-trans isomerase FKBP8; PPIase FKBP8; 38 kDa FK506-binding protein; 38 kDa FKBP; FKBP-38; hFKBP38; FK506-binding protein 8; FKBP-8; FKBPR38; Rotamase; FKBP8; FKBP38] |
Gene, Accession # | [FKBP8], Gene ID: 23770, NCBI: NP_001295302.1, UniProt: Q14318 |
Catalog # | MBS7050156 |
Price | $160, $235 |
Order / More Info | FKBP8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |