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Antigenic Specificity | NEFL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total NEFL antibody. The cytoskeleton consists of three types of cytosolic fibers: actin microfilaments, intermediate filaments, and microtubules. Neurofilaments are the major intermediate filaments found in neurons and consist of light (NFL), medium (NFM), and heavy (NFH) subunits (1). Similar in structure to other intermediate filament proteins, neurofilaments have a globular amino-terminal head, a central a-helical rod domain, and a carboxy-terminal tail. A heterotetrameric unit (NFL-NFM and NFL-NFH) forms a protofilament, with eight protofilaments comprising the typical 10 nm intermediate filament (2). While neurofilaments are critical for radial axon growth and determine axon caliber, microtubul |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant Protein of human NEFL. |
Other Names | [NEFL; CMT1F; CMT2E; NF L; NFL; 68 kDa neurofilament protein] |
Gene, Accession # | [NEFL], Gene ID: 4747, NCBI: NP_006149.2, UniProt: P07196 |
Catalog # | MBS9406645 |
Price | $255 |
Order / More Info | NEFL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |