Lipid A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLipid A
Clone26-5
Host SpeciesMouse
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunoassay
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DescriptionThe monoclonal antibody 26-5 recognizes lipid A. The lipid A domain of lipopolysaccharide (LPS) is a unique, glucosamine-based phospholipid that makes up the outer monolayer of the outer membrane of most gram-negative bacteria. Lipid A is responsible for the endotoxic activities of LPS, and a heteropolysaccharide. The heteropolysaccharide generally consists of an oligosaccharide termed the core region. This core region is in some bacterial families composed of repeating oligosaccharide units, the so-called O chain. The lipid A moiety of LPS is detected by the TLR4/MD2 receptor of the mammalian innate immune system. Picomolar levels of lipid A induce macrophages to synthesize potent mediators of inflammation, such as TNF-alpha and IL-1beta.
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS584826
Price$610
Order / More InfoLipid A Antibody from MYBIOSOURCE INC.
Product Specific ReferencesErich, T et al; Binding characteristics and cross-reactivity of three different antilipid A monoclonal antibodies. J of Immunol 1989, 143: 4053.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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