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Antigenic Specificity | n-Myc (Neuroblastoma Marker) |
Clone | [NMYC-1] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-heli |
Immunogen | Immunogen: Recombinant full-length human n-Myc protein. |
Other Names | [Class E basic helix-loop-helix protein 37 (bHLHe37); MODED; N-myc proto-oncogene protein; Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene; ODED; pp65/67; v myc (avian) myelocytomatosis viral related oncogene neuroblastoma derived] |
Gene, Accession # | [MYCN], Gene ID: 4613, NCBI: NP_005369.2, UniProt: P04198 |
Catalog # | MBS4381110 |
Price | $190, $340, $340 |
Order / More Info | n-Myc (Neuroblastoma Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Schwab, M., et al. 1983. Nature 305: 245-248. |