n-Myc (Neuroblastoma Marker) Antibody from MYBIOSOURCE INC.

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Antigenic Specificityn-Myc (Neuroblastoma Marker)
Clone[NMYC-1]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2a, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunofluorescence (IF), Western Blot (WB)
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DescriptionThe v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-heli
ImmunogenImmunogen: Recombinant full-length human n-Myc protein.
Other Names[Class E basic helix-loop-helix protein 37 (bHLHe37); MODED; N-myc proto-oncogene protein; Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene; ODED; pp65/67; v myc (avian) myelocytomatosis viral related oncogene neuroblastoma derived]
Gene, Accession #[MYCN], Gene ID: 4613, NCBI: NP_005369.2, UniProt: P04198
Catalog #MBS4381110
Price$190, $340, $340
Order / More Infon-Myc (Neuroblastoma Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSchwab, M., et al. 1983. Nature 305: 245-248.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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