RAT MEK 5 (pSer311/Thr315) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-RAT MEK 5 (pSer311/Thr315) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | RAT MEK 5 (pSer311/Thr315) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | bovine (expected from sequence), chicken (expected from sequence), dog (expected from sequence), human (expected from sequence), mouse (expected from sequence), primate (expected from sequence), Xenopus (expected from sequence), zebrafish (expected from S |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB)* |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item specifically recognises 49kDa MEK5, also known as MAP2K5, when phosphorylated at Ser311 and Thr315. . . MEK5 is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family, which acts as a key regulator in a mitogen-activated protein (MAP) kinase cascade, and hence growth factor-induced cellular stimulation. MEK5 exists in naturally occurring MEK5alpha and MEK5beta splice variants, the former of which is known to specifically activate/regulate MAPK7/ERK5/BMK1, whilst the latter may act as a suppressor of MAPK7 activation. Activation of MEK5 itself is regulated by upstream MAP3K3/MEKK3, and phosphorylation of MEK5 at both the Ser311 and Thr315 sites has been implicated in cell proliferation. MBS22 |
| Immunogen | Immunogen: Synthetic phosphopeptide corresponding to an amino acid sequence within MEK5, which includes phoshorylated Ser311 and Thr315. Buffer Solution: 10mM Hepes pH7.5 Antiserum Preparation: Antisera to MEK5 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Rat |
| Other Names | [dual specificity mitogen-activated protein kinase kinase 5 isoform a; Dual specificity mitogen-activated protein kinase kinase 5; dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPK/ERK kinase 5; MAPKK 5; MEK 5; mitogen activated protein kinase kinase 5; MAPK/ERK kinase 5; MEK 5], [Map2k5; Map2k5; Mek5; Mek5; Mkk5; Prkmk5; MAP kinase kinase 5; MAPKK 5; MEK 5] |
| Gene, Accession # | [MEK 5], Gene ID: 29568, NCBI: NP_001029159.1, UniProt: Q62862 |
| Catalog # | MBS222783 |
| Price | $550 |
| Order / More Info | RAT MEK 5 (pSer311/Thr315) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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