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Antigenic Specificity | SOD1 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Superoxide dismutase [Cu-Zn](SOD1) detection. Tested with WB in Human;Mouse;Rat. Background: Superoxide dismutases (SOD) are a class of enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. As such, they are an important antioxidant defense in nearly all cells exposed to oxygen. One of the exceedingly rare exceptions is Lactobacillus plantarum and related lactobacilli, which use a different mechanism.Cu,Zn-SOD was found widely distributed in the cell cytosol and in the cell nucleus, consistent with it being a soluble cytosolic protein. Mitochondria and secretory compartments did not label for this protein. In human cells, peroxisomes showed a labeling density s |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of Human SOD1 (116-146aa RTLVVHEKADDLGKGGNEESTKTGNAGSRLA), different from the related mouse and rat sequences by two amino acids. Ig Type: Rabbit IgG |
Other Names | [Superoxide dismutase [Cu-Zn]; ALS 1; ALS; ALS1; Amyotrophic lateral sclerosis 1 adult; Amyotrophic lateral sclerosis 1; Cu/Zn SOD; Cu/Zn superoxide dismutase; Homodimer; hSod1; Indophenoloxidase A; IPOA; Mn superoxide dismutase; SOD 1; SOD; SOD soluble; SOD1; SODC; SODC_HUMAN; Superoxide dismutase [Cu Zn]; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; Superoxide dismutase 1 soluble; Superoxide dismutase; Superoxide dismutase Cu Zn; Superoxide dismutase cystolic; superoxide dismutase 1, soluble], [SOD1; SOD1; ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer; hSod1] |
Gene, Accession # | [SOD1], Gene ID: 6647, NCBI: NP_000445.1, UniProt: P00441 |
Catalog # | MBS178103 |
Price | $280 |
Order / More Info | SOD1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Crapo, J. D., Oury, T., Rabouille, C., Slot, J. W., Chang, L.-Y. Copper,zinc superoxide dismutase is primarily a cytosolic protein in human cells. Proc. Nat. Acad. Sci. 89: 10405-10409, 1992. |