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Antigenic Specificity | JAK2, phosphorylated (Tyr1007) Tyrosine-protein Kinase JAK2, Janus Kinase 2, JAK-2) |
Clone | [D15E2] |
Host Species | Rabbit |
Reactive Species | human, monkey, mouse, rat |
Isotype | IgG |
Format | supernatant |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes endogenous levels of human Jak2 when phosphorylated at Tyr1007. It can also detect double phosphorylation at Tyr1007 and Tyr1008. Cross-reactivity may be observed with phosphorylated Jak3 and Tyk2. Species Crossreactivity: Monkey, mouse and rat. Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3 and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4) and focal adhesion kinase (FAK) (5), typically contain SH2 o |
Immunogen | Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Tyr1007 of human Jak2. |
Other Names | [-JAK2, phosphorylated (Tyr1007) Tyrosine-protein Kinase JAK2, Janus Kinase 2, JAK-2)] |
Gene, Accession # | Gene ID: 30298, NCBI: BAH47262.1 |
Catalog # | MBS6008461 |
Price | $595 |
Order / More Info | JAK2, phosphorylated (Tyr1007) Tyrosine-protein Kinase JAK2, Janus Kinase 2, JAK-2) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |