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Antigenic Specificity | Human CCKBR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | DyLight 488 conjugate |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. The cholecystokinin B receptor, also known as CCKBR or CCK2, is a protein that in humans is encoded by the CCKBR gene. This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human CCKBR (PVYTVVQPVGPRVLQCVHRWPSARVRQTWS). |
Other Names | [Rabbit IgG Human CCKBR DyLight 488 Conjugated, Flow Validated; Gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; Cholecystokinin-2 receptor; CCK2-R; CCKBR; CCKRB; Cholecystokinin B receptor] |
Gene, Accession # | [CCKBR], Gene ID: 887, NCBI: NP_001304958.1, UniProt: P32239 |
Catalog # | MBS1751371 |
Price | $330 |
Order / More Info | Human CCKBR Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Altar CA, Boyar WC (Apr 1989). Brain CCK-B receptors mediate the suppression of dopamine release by cholecystokinin. Brain Research. 483 (2): 321-6. 2. Noble F, Roques BP (Jul 1999). CCK-B receptor: chemistry, molecular biology, biochemistry and pharmacology. Progress in Neurobiology. 58 (4): 349-79. |