GluN1-NR1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | GluN1-NR1 |
| Clone | [S308-48] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | alkaline phosphatase (AP) conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects ~105kDa Scientific Background: The NMDA receptor (NMDAR), a glutamate receptor, is the predominant molecular device for controlling synaptic plasticity and memory function (1). The NMDA receptor forms a heterotetramer between two NR1 and two NR2 subunits (the subunits are also called glutamate-binding NMDA receptor subunits or GluN for short); two obligatory NR1 subunits and two regionally localized NR2 subunits. A related gene family of NR3 A and B subunits have an inhibitory effect on receptor activity. Multiple receptor isoforms with distinct brain distributions and functional properties arise by selective splicing of the NR1 transcripts and differential expression of the NR2 subunits. |
| Immunogen | n/a |
| Other Names | [NMDAR1; NMDA Receptor 1; NMDAR; NMDA1; GRIN1; Glutamate [NMDA] receptor subunit zeta-1; Glutamate receptor ionotropic N methyl D aspartate 1; MRD8; N methyl D aspartate receptor; N methyl D aspartate receptor channel subunit zeta 1; NR1], [Grin1; Grin1; NR1; GluN1; NMDAR1; Nmdar1; GluN1; NMD-R1] |
| Gene, Accession # | Gene ID: 24408, NCBI: NP_058706.1, UniProt: P35439 |
| Catalog # | MBS800281 |
| Price | $430 |
| Order / More Info | GluN1-NR1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Li F., and Tsien J.Z. (2009) Clinical Implications of Basic Research: Memory and the NMDA receptors. New England J. Medicine. 361: 302-303. 2. Garcia-Gallo M., Renart J., Diaz-Guerra M. (2001) Biochem J. 356: 539-547. 3. Atlason P.T., Garside M.L., Meddows E., Whiting P., McIllhinney R.A.J. (2007) J Biol Chem. 282(35): 25299-25307. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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