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Antigenic Specificity | K2C1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: K2C1 antibody detects endogenous levels of total K2C1. Function: May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.Subunit Structure: Heterotetramer of two type I and two type II keratins. Heterodimer with KRT10 (PubMed:27595935). Two heterodimers of KRT1 and KRT10 form a heterotetramer (PubMed:27595935). Interacts with ITGB1 in the presence of RACK1 and SRC, and with RACK1 (PubMed:17956333). Interacts with C1QBP; the association represents a cell surface kininogen receptor (PubMed:21544310). Interacts with EPPK1; interaction is dependent of higher-orde |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane. Located on plasma membrane of neuroblastoma NMB7 cells. Tissue Specificity: The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis. Predicted Cross Reactivity: Horse Similarity: Horse (83%) |
Other Names | [67 kDa cytokeratin; CK-1; CK1; Cytokeratin 1; Cytokeratin 19; Cytokeratin 8; Cytokeratin-1; EHK; EHK1; epidermolytic hyperkeratosis 1; EPPK; Hair alpha protein; K1; K2C1_HUMAN; KB1; Keratin 1; keratin 1, type II; Keratin 19; Keratin 8; Keratin; keratin, type II cytoskeletal 1; Keratin-1; Krt1; KRT19; KRT1A; KRT8; KRTA; NEPPK; type II cytoskeletal 1; Type-II keratin Kb1] |
Gene, Accession # | [K2C1], Gene ID: 3848, NCBI: NP_006112.3, UniProt: P04264 |
Catalog # | MBS9604068 |
Price | $240, $280 |
Order / More Info | K2C1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |