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Antigenic Specificity | Human GDF-15 |
Clone | [10A3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GDF-15 belongs to the TGF-beta cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in placenta and to a much lesser extent in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest a role for GDF-15 in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certa |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of GDF-15. |
Other Names | [GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15], [GDF15; GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; MIC1; PDF; PLAB; PTGFB; GDF-15; MIC-1; NAG-1; NRG-1] |
Gene, Accession # | [GDF-15], Gene ID: 9518, NCBI: NP_004855.2, UniProt: Q99988 |
Catalog # | MBS690740 |
Price | $490 |
Order / More Info | Human GDF-15 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |