alpha-Actinin 4 (Tyr-4), Phospho-Specific Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-alpha-Actinin 4 (Tyr-4), Phospho-Specific antibody, protein, ELISA kits.
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| Antigenic Specificity | alpha-Actinin 4 (Tyr-4), Phospho-Specific |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects a 100 kDa* protein corresponding to the molecular mass of alpha-actinin 4 on SDS-PAGE immunoblots of human A431 cells treated with pervanadate, but is not observed after akaline phosphatase treatment. alpha-Actinins are widely expressed cytoskeletal proteins that cross-link actin filaments through anti-parallel homodimers of the rod domains. Four alpha-actinin genes have been discovered in humans with alpha-actinin 1 and 4 being widely expressed in non-muscle cells. alpha-Actinins contain three conserved domains that include an N-terminal actin binding domain, four spectrin-like repeats in the central region, and a C-terminal calmodulin binding domain. alpha-Actinin cross-links the actin filament networks and associates |
| Immunogen | Immunogen: Phospho-alpha-actinin 4 (Tyr-4) synthetic peptide (coupled to carrier protein) corresponding to amino acids in the N-terminus of human alpha-actinin 4. This sequence is well conserved in rat and mouse alpha-actinin 4, but is not conserved in other alpha-actinins. |
| Other Names | [actinin alpha4], [ACTN4; ACTN4; FSGS; FSGS1; ACTININ-4] |
| Gene, Accession # | Gene ID: 81, NCBI: O43707.2, UniProt: O43707 |
| Catalog # | MBS474081 |
| Price | $385 |
| Order / More Info | alpha-Actinin 4 (Tyr-4), Phospho-Specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kojima, S. et al. (2014) Am J Nephrol. 39(1):36-45. Izaguirre, G. et al. (2001) J Biol Chem. 276(31):28676. Ylanne et al. (2001) Structure. 9:597. Shao, H. et al. (2010) J Biol Chem. 285(4):2591. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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