KDM1B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKDM1B
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.05 mL
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionPolyclonal Antibody to detect KDM1B in human samples. Background: KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently
ImmunogenImmunogen: Polyclonal antibody raised in rabbit against human KDM1B (lysine (K)-specific demethylase 1B) using two KLH conjugated synthetic peptides containing a sequence from the N-terminal and the central region of the protein, respectively. Positive Control: ELISA: Peptides.
Other Names[AOF1; LSD2; C6orf193], [KDM1B; KDM1B; AOF1; LSD2; C6orf193; bA204B7.3; dJ298J15.2; AOF1; C6orf193; LSD2]
Gene, Accession #[KDM1B], Gene ID: 221656, NCBI: NP_694587.3, UniProt: Q8NB78
Catalog #MBS840810
Price$235
Order / More InfoKDM1B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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