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Antigenic Specificity | KDM1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect KDM1B in human samples. Background: KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently |
Immunogen | Immunogen: Polyclonal antibody raised in rabbit against human KDM1B (lysine (K)-specific demethylase 1B) using two KLH conjugated synthetic peptides containing a sequence from the N-terminal and the central region of the protein, respectively. Positive Control: ELISA: Peptides. |
Other Names | [AOF1; LSD2; C6orf193], [KDM1B; KDM1B; AOF1; LSD2; C6orf193; bA204B7.3; dJ298J15.2; AOF1; C6orf193; LSD2] |
Gene, Accession # | [KDM1B], Gene ID: 221656, NCBI: NP_694587.3, UniProt: Q8NB78 |
Catalog # | MBS840810 |
Price | $235 |
Order / More Info | KDM1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |