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Antigenic Specificity | Human CD35 |
Clone | [4AE11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 4AE11 reacts with CR1, the receptor for the complement component C3b/C4, composed of four different allotypes (160, 190, 220 and 150 kDa). CD35 antigen is expressed on erythrocytes, neutrophils, monocytes, B-lymphocytes and 10-15% of T-lymphocytes. CD35 is catagorized as a regulator of complement avtivation. It binds complement components C3b and C4b, mediating phagocytosis by granulocytes and monocytes. Application: Removal and reduction of excessive amounts of complement fixing immune complexes in SLE and other auto-immune disorder.This clone is cross reactive with non-human primate. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [CD35] |
Catalog # | MBS8500439 |
Price | $280, $300 |
Order / More Info | Human CD35 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Ling NR et al., eds. (1987) Leucocyte Typing III: White Cell Differentiation Antigens, Oxford University Press, New York. 303-334. 2.Schlossman, SL et al., eds. (1995) Leucocyte TypingV: White Cell Differentiation Antigens, Oxford University Press, New York. 3.Ahearn JM, (1989) Adv Immunol 46:183. |