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Antigenic Specificity | LMNA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment (3, 4). The cleavage of lamins results in nuclear disregulation and cell death (5, 6). |
Immunogen | Immunogen: Recombinant protein of human LMNA Observed Molecular Weight: 65kDa |
Other Names | [LMNA; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1] |
Gene, Accession # | [LMNA], Gene ID: 4000, NCBI: NP_001244303.1 |
Catalog # | MBS2519160 |
Price | $150, $225, $360 |
Order / More Info | LMNA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |