SOD1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SOD1 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | SOD1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen (1). SOD1 is ubiquitously expressed and is localized in the cytosol, nucleus and mitochondrial intermembrane space. The SOD1 gene locus is on chromosome 21 in a region affected in Down Syndrome (2). In addition, over 100 distinct SOD1 inherited mutations have been identified in the familial form of amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons (3-5). Despite the fact that SOD1 helps to eliminate toxic reactive species, its mutations in ALS have been described as gain-of-function (5). The mechanism by which mutant SOD1 induces the neurodegenerati |
| Immunogen | Immunogen: Recombinant protein of human SOD1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [SOD1; ALS; ALS1; IPOA; SOD; homodimer] |
| Gene, Accession # | [SOD1], Gene ID: 6647, NCBI: NP_000445.1, UniProt: P00441 |
| Catalog # | MBS8503908 |
| Price | $310 |
| Order / More Info | SOD1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. McCord, J.M. and Fridovich, I. (1988) Free Radic Biol Med 5, 363-9. 2. Sherman, L. et al. (1983) Proc Natl Acad Sci USA 80, 5465-9. 3. Rosen, D.R. et al. (1993) Nature 362, 59-62. 4. Deng, H.X. et al. (1993) Science 261, 1047-51. 5. Valentine, J.S. and Hart, P.J. (2003) Proc Natl Acad Sci USA 100, 3617-22. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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