Edit |   |
---|---|
Antigenic Specificity | HXK I |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HXK I Polyclonal Antibody detects endogenous levels of HXK I protein. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. HK1 encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in HK1 have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human HXK I at AA range: 1-80 |
Other Names | [Rabbit HXK I; Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I] |
Gene, Accession # | [HK1], Gene ID: 3098, NCBI: NP_000179.2, UniProt: P19367 |
Catalog # | MBS9702286 |
Price | $130, $220, $325 |
Order / More Info | HXK I Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |