Human heparanase Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman heparanase
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse;
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.15 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionEndoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group. Can also cleave the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying a 2-O-sulfo group, but not linkages between a glucuronic acid unit and a 2-O-sulfated iduronic acid moiety. It is essentially inactive at neutral pH but becomes active under acidic conditions such as during tumor invasion and in inflammatory processes. Facilitates cell migration associated with metastasis, wo
ImmunogenImmunogen: Human HPSE. Conjugate : Non-conjugated
Other Names[Endo-glucoronidase, Heparanase-1, HEP, HPA, HPA1, HPR1, HPSE1, HSE1, HPSE], [HPSE; HPSE; HPA; HPA1; HPR1; HSE1; HPSE1; HEP; HPA; HPA1; HPR1; HPSE1; HSE1; Hpa1]
Gene, Accession #Gene ID: 10855, NCBI: AAD54941.1
Catalog #MBS711555
Price$230, $500
Order / More InfoHuman heparanase Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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