MAGED1 (Center) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MAGED1 (Center) |
| Clone | [1305CT862.157.127] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1,kappa |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAGED1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 20-224 amino acids from the Central region of human MAGED1. Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds NGFR/p75NTR and antagonizes its association with NTRK1/TrkA, inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate TP53/p53 transcriptional activity and inhibit cell proliferation. Enhances TP53 phosphorylation and accumulation. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization |
| Immunogen | n/a |
| Other Names | [Melanoma-associated antigen D1; MAGE tumor antigen CCF; MAGE-D1 antigen; Neurotrophin receptor-interacting MAGE homolog; MAGED1; NRAGE] |
| Gene, Accession # | [MAGED1], Gene ID: 9500, NCBI: NP_001005332.1, UniProt: Q9Y5V3 |
| Catalog # | MBS9200239 |
| Price | $165, $370 |
| Order / More Info | MAGED1 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Salehi A.H.,et al.Neuron 27:279-288(2000). Wen C.-J.,et al.FEBS Lett. 564:171-176(2004). Chen Y.,et al.Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. Ross M.T.,et al.Nature 434:325-337(2005). Pold M.,et al.Genomics 59:161-167(1999). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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