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Antigenic Specificity | CD6 (Negative Marker of T-regulatory Cells) |
Clone | [C6/2884R] |
Host Species | Rabbit |
Reactive Species | human. |
Isotype | IgG |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistology (Formalin-Fixed) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease. Recombinant Rabbit Monoclonal Antibody |
Immunogen | Immunogen: Human recombinant full-length CD6 protein Positive Control: CCRF-CEM, Jurkat Cells, Tonsil |
Other Names | [T12; TP120] |
Gene, Accession # | [CD6], Gene ID: 923, NCBI: NP_001241679.1, UniProt: P30203 |
Catalog # | MBS4380736 |
Price | $190, $340, $340 |
Order / More Info | CD6 (Negative Marker of T-regulatory Cells) Antibody from MYBIOSOURCE INC. |
Product Specific References | Bazil, V et. al. 1989. Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102. Folia. Biol. 35:289-297. |