Human CD49d Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD49d
Clone[HP2/1]
Host SpeciesMouse
Reactive Speciesbovine, cat, cynomolgus monkey, goat, horse, llama, mink, mustelid, porcine, rabbit, rat, rhesus monkey
IsotypeIgG1
Formatunconjugated
Size0.2 mg
ConcentrationIgG concentration 1 mg/ml
ApplicationsImmunohistology Frozen, Flow cytometry (FC/FACS), Functional Assays (FN)*, Immunoprecipitation (IP)
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DescriptionMouse anti Human CD49d monoclonal antibody, clone HP2/1 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ~150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer's patch high endothelial venules and postcapillary venules in la
Immunogenn/a
Other Names[integrin alpha-4; Integrin alpha-4; integrin alpha-4; 269C wild type; CD49 antigen-like family member D; VLA-4 subunit alpha; antigen CD49D, alpha-4 subunit of VLA-4 receptor; integrin alpha 4; integrin alpha-4 subunit; integrin alpha-IV; very late activation protein 4 receptor, alpha 4 subunit; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alpha; CD_antigen: CD49d], [ITGA4; ITGA4; IA4; CD49D; CD49D]
Gene, Accession #[CD49d], Gene ID: 3676, NCBI: NP_000876.3, UniProt: P13612
Catalog #MBS213115
Price$430
Order / More InfoHuman CD49d Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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