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Antigenic Specificity | Human SURVIVIN (C-TERMINAL) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item specifically recognises an epitope within the C-terminal (CT) region of human Survivin, otherwise known as TIAP/BIRC5, a novel inhibitor of apoptosis (IAP) protein, and component of the chromosomal passenger complex, which plays a key role in the regulation of mitosis.. . Survivin is only expressed during the G2-M cell cycle phase, and is predominantly expressed in foetal tissues, and in many human cancers, including adenocarcinomas and high-grade lymphomas. The lack of survivin expression by normal non-malignant cells, makes survivin an important therapeutic target for cancer. MBS224113 specifically recognises an epitope within the C-terminal (CT) region of human Survivin, otherwise known as TIAP/BIRC5, a novel inhibitor of apo |
Immunogen | Immunogen: Synthetic peptide sequence CVRRAIEQLAAMD from the C-Terminal region of Survivin (NP 001159.2; NP 001012271.1). Buffer Solution: TRIS buffered saline Antiserum Preparation: Antiserum to human Survivin (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human |
Other Names | [baculoviral IAP repeat-containing protein 5 isoform 2; Baculoviral IAP repeat-containing protein 5; baculoviral IAP repeat-containing protein 5; apoptosis inhibitor 4; apoptosis inhibitor survivin; survivin variant 3 alpha; baculoviral IAP repeat containing 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin], [BIRC5; BIRC5; API4; EPR-1; API4; IAP4] |
Gene, Accession # | Gene ID: 332, NCBI: NP_001012270.1, UniProt: O15392 |
Catalog # | MBS224113 |
Price | $550 |
Order / More Info | Human SURVIVIN (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |