Human SURVIVIN (C-TERMINAL) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman SURVIVIN (C-TERMINAL)
Clonepolyclonal
Host SpeciesGoat
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 0.5mg/ml
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionThis item specifically recognises an epitope within the C-terminal (CT) region of human Survivin, otherwise known as TIAP/BIRC5, a novel inhibitor of apoptosis (IAP) protein, and component of the chromosomal passenger complex, which plays a key role in the regulation of mitosis.. . Survivin is only expressed during the G2-M cell cycle phase, and is predominantly expressed in foetal tissues, and in many human cancers, including adenocarcinomas and high-grade lymphomas. The lack of survivin expression by normal non-malignant cells, makes survivin an important therapeutic target for cancer. MBS224113 specifically recognises an epitope within the C-terminal (CT) region of human Survivin, otherwise known as TIAP/BIRC5, a novel inhibitor of apo
ImmunogenImmunogen: Synthetic peptide sequence CVRRAIEQLAAMD from the C-Terminal region of Survivin (NP 001159.2; NP 001012271.1). Buffer Solution: TRIS buffered saline Antiserum Preparation: Antiserum to human Survivin (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human
Other Names[baculoviral IAP repeat-containing protein 5 isoform 2; Baculoviral IAP repeat-containing protein 5; baculoviral IAP repeat-containing protein 5; apoptosis inhibitor 4; apoptosis inhibitor survivin; survivin variant 3 alpha; baculoviral IAP repeat containing 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin], [BIRC5; BIRC5; API4; EPR-1; API4; IAP4]
Gene, Accession #Gene ID: 332, NCBI: NP_001012270.1, UniProt: O15392
Catalog #MBS224113
Price$550
Order / More InfoHuman SURVIVIN (C-TERMINAL) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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