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Antigenic Specificity | UHRF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to Human UHRF1. UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitinprotein ligase. It may participate in methylationdependent transcriptional regulation. UHRF1 binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2. This gene encodes a member of a subfamily of RINGfinger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues dur |
Immunogen | Immunogen: A fusion protein of human UHRF1 |
Other Names | [UHRF1; UHRF1; FLJ21925; ICBP90; MGC138707; Np95; RNF106; hNP95;], [UHRF1; UHRF1; Np95; hNP95; ICBP90; RNF106; hUHRF1; ICBP90; NP95; RNF106; HuNp95; hNp95; hUHRF1] |
Gene, Accession # | Gene ID: 29128, NCBI: NP_001041666.1, UniProt: Q96T88 |
Catalog # | MBS126064 |
Price | $275, $430 |
Order / More Info | UHRF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |