P21 Mouse Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityP21 Mouse
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, mouse, monkey.
IsotypeIgG1
FormatProtein A purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: Please decide specifity by homology. CDKN1A (p21, CIP1, WAF1), a cyclin-dependent kinase inhibitor, is necessary for proper control of the cell cycle and premature senescence. P21 is a cyclin-dependent kinase (CDK) inhibitor that suppresses proliferation by inhibiting CDK2 and CDK1 activity at the G1/S and G2/M transitions. P21 is a major mediator of p53 to induce cell cycle arrest in G1. p21 can interact with proliferating cell nuclear antigen (PCNA), and plays a regulatory role in S phase DNA replication and DNA damage repair. P21 was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation.
ImmunogenImmunogen: Cyclin-dependent kinase inhibitor 1A (p21, Cip1) Calculated MW: 21 kDa
Other Names[CAP20, CDK interacting protein 1, CDKN1, CDKN1A, CIP1, MDA 6, MDA6, P21, p21CIP1, PIC1, SDI1, WAF1]
Gene, Accession #[P21], Gene ID: 1026, NCBI: AAB29246.1, UniProt: P38936
Catalog #MBS7602299
Price$290
Order / More InfoP21 Mouse Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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